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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
33.94
Human Site:
S511
Identified Species:
49.78
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
S511
G
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
Chimpanzee
Pan troglodytes
XP_520198
559
62217
S548
G
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
S510
G
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
Dog
Lupus familis
XP_532038
521
58332
S510
G
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
S510
G
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
Rat
Rattus norvegicus
Q5BK30
415
45841
G405
K
G
N
I
V
I
T
G
S
K
D
N
S
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
Y380
Q
L
I
A
T
C
S
Y
D
R
T
F
K
L
W
Chicken
Gallus gallus
Q5ZMA2
505
55116
G495
A
K
F
I
A
S
T
G
M
D
R
S
L
K
F
Frog
Xenopus laevis
Q5FWQ6
415
45899
G405
E
G
N
T
I
I
T
G
S
K
D
N
T
C
R
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
G405
E
G
D
T
I
I
T
G
S
K
D
N
T
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
S400
H
P
Y
V
I
S
G
S
V
D
Q
T
V
K
V
Honey Bee
Apis mellifera
XP_393186
525
59172
S512
H
R
F
I
G
T
S
S
Y
D
R
T
F
K
L
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
S482
A
R
S
L
V
T
C
S
L
D
K
S
L
R
V
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
S491
E
K
Y
I
A
T
S
S
F
D
R
T
F
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
S527
S
S
C
I
A
T
V
S
H
D
R
T
I
K
L
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
G455
N
S
H
F
L
V
S
G
G
W
D
R
S
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
33.3
0
0
N.A.
26.6
66.6
26.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
53.3
0
0
N.A.
53.3
73.3
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
50
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
7
38
0
0
0
0
0
0
19
0
% C
% Asp:
0
0
7
0
0
0
0
0
7
69
25
0
0
0
0
% D
% Glu:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
7
0
0
0
0
7
0
0
7
44
0
7
% F
% Gly:
32
19
0
0
7
0
7
32
7
0
0
0
0
0
0
% G
% His:
13
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
63
19
19
0
0
0
0
0
0
7
7
0
% I
% Lys:
7
13
0
0
0
0
0
0
0
19
7
0
7
63
7
% K
% Leu:
0
7
32
7
7
0
0
0
7
0
0
0
13
7
50
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
13
0
0
0
0
0
0
0
0
19
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
32
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
7
57
7
0
7
19
% R
% Ser:
7
13
7
0
0
13
25
63
19
0
0
13
13
0
0
% S
% Thr:
0
0
0
13
7
57
25
0
0
0
7
57
13
0
0
% T
% Val:
0
0
0
7
13
7
7
0
7
0
0
0
7
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
13
0
0
0
0
7
38
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _